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REVIEW ARTICLE
Year : 2009  |  Volume : 10  |  Issue : 4  |  Page : 145-155

Major bleeding in acute coronary syndrome


1 MB CH B, F.R.C.P.; F.E. S. C., Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation (HMC), Doha, Qatar
2 MB, ChB, F.A.C.C.; F.S.C.A.I.; F.E.S.C., Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation (HMC), Doha, Qatar

Correspondence Address:
Douraid K Shakir
Director of the Cardiac Catheterization Laboratory, Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation, P.O Box 3050, Doha
Qatar
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Source of Support: None, Conflict of Interest: None


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Acute coronary syndrome forms the vast majority of cases faced in daily cardiology clinical practice. It is usually managed by antiplatelates, antithrombotics and anticoagulants, all of which increase the risk of bleeding with associated increment in morbidity and mortality. Data gained from many studies and registries all over the world try to explore the magnitude of such problem as well as predictors and management. The definition of major bleeding in acute coronary syndrome is a dilemma by itself, as different definitions have led to inconsistency in its reported prevalence and magnitude of sequelae. Predicting the occurrence of major bleeding may help in saving lives, improving outcomes and cost-savings by preventing it. In this review, we try to explore these issues based on data extracted from large numbers of trials, studies and registries.


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