The gulf implantable cardioverter-defibrillator registry: Rationale, methodology, and implementation
Alawi A Alsheikh-Ali1, Ahmad S Hersi2, Adel K. S. Hamad3, Ahmed R Al Fagih4, Faisal M Al-Samadi5, Abdulmohsen M Almusaad6, Fayez A Bokhari7, Fawzia Al-Kandari8, Bandar S Al-Ghamdi9, Najib Al Rawahi10, Nidal Asaad11, Salem Alkaabi12, Amin Daoulah13, Hosam A Zaky14, Omer Elhag15, Yahya S Al Hebaishi4, Raed Sweidan7, Haitham Alanazi6, David Chase10, Hani Sabbour15, Mohammad Al Meheiri15, Ismail Al Abri10, Mohammad Amin3, Khaled Dagriri4, Adil O Ahmed4, Azam Shafquat9, Shahul Hameed Khan11
1 Division of Adult Cardiology, Institute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates
2 Department of Cardiac Sciences, King Khalid University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia
3 Mohammed Bin Khalifa Bin Sulman AlKhalifa Cardiac Center, Bahrain Defense Force Hospital, Manama, Kingdom of Bahrain
4 Prince Sultan Cardiac Center, King Fahd Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia
5 King Salman Heart Center, King Fahd Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia
6 King Abdulaziz Cardiac Center, King Abdulaziz Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia
7 Division of Adult Cardiology, King Fahd Armed Forces Hospital, Jeddah, Kingdom of Saudi Arabia
8 Division of Adult Cardiology, Chest Hospital, Kuwait Cardiac Center and Dabbous Cardiac Center, Kuwait City, Kuwait
9 Heart Center, King Faisal Specialist Hospital and Research Center, College of Medicine, Alfaisal University, Riyadh, Kingdom of Saudi Arabia
10 Division of Adult Cardiology, Royal Hospital, Muscat, Oman
11 Division of Adult Cardiology, Heart Hospital, Hamad Medical Corporation, Doha, Qatar
12 Division of Adult Cardiology, Zayed Military Hospital, Abu Dhabi, United Arab Emirates
13 Division of Adult Cardiology, King Faisal Specialist Hospital, Jeddah, Kingdom of Saudi Arabia
14 Division of Adult Cardiology, Dubai Hospital, Dubai, United Arab Emirates
15 Division of Adult Cardiology, Institute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates
Alawi A Alsheikh-Ali
Institute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi
United Arab Emirates
Source of Support: None, Conflict of Interest: None
Background: The implantable cardioverter-defibrillator (ICD) is effective in the prevention of sudden cardiac death in high-risk patients. Little is known about ICD use in the Arabian Gulf. We designed a study to describe the characteristics and outcomes of patients receiving ICDs in the Arab Gulf region.
Methods: Gulf ICD is a prospective, multi-center, multinational, and observational study. All adult patients 18 years or older, receiving a de novo ICD implant and willing to sign a consent form will be eligible. Data on baseline characteristics, ICD indication, procedure and programing, in-hospital, and 1-year outcomes will be collected. Target enrollment is 1500 patients, which will provide adequate precision across a wide range of expected event rates.
Results: Fifteen centers in six countries are enrolling patients (Saudi Arabia, United Arab Emirates, Kuwait, Oman, Bahrain, and Qatar). Two-thirds of the centers have dedicated electrophysiology laboratories, and in almost all centers ICDs are implanted exclusively by electrophysiologists. Nearly three-quarters of the centers reported annual ICD implant volumes of ≤150 devices, and pulse generator replacements constitute <30% of implants in the majority of centers. Enrollment started in December 2013, and accrual rate increased as more centers entered the study reaching an average of 98 patients per month.
Conclusions: Gulf ICD is the first prospective, observational, multi-center, and multinational study of the characteristics and, the outcomes of patients receiving ICDs in the Arab Gulf region. The study will provide valuable insights into the utilization of and outcomes related to ICD therapy in the Gulf region.