Outcomes of Middle Eastern patients undergoing percutaneous coronary intervention: The primary analysis of the First Jordanian PCI Registry
Imad A Alhaddad1, Ramzi Tabbalat2, Yousef Khader3, Eyas Al-Mousa4, Mahmoud Izraiq5, Assem Nammas6, Mohammad Jarrah7, Akram Saleh8, Ayman Hammoudeh4, On behalf of the First Jordanian PCI Registry Investigators Group9
1 Department of Cardiovascular, Jordan Hospital, Amman, Jordan
2 Department of Cardiology, Khalidi Medical Center, Amman, Jordan
3 School of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, Jordan
4 Department of Cardiology, Istishari Hospital, Amman, Jordan
5 Department of Cardiology, Specialty Hospital, Amman, Jordan
6 Department of Cardiology, Ibn Al-Haytham Hospital, Amman, Jordan
7 Department of Internal Medicine, Jordan University of Science and Technology, King Abdullah University Hospital, Irbid, Jordan
8 Department of Internal Medicine, Jordan University of Jordan School of Medicine, Amman, Jordan
Dr. Imad A Alhaddad
Queen Nour Street, Amman 11152
Source of Support: None, Conflict of Interest: None
Aim: This is a prospective multicenter registry designed to evaluate the incidence of adverse cardiovascular events in Middle Eastern patients undergoing percutaneous coronary interventions (PCI). The registry was also designed to determine the predictors of poor outcomes in such patients.
Methods and Results: We enrolled 2426 consecutive patients who underwent PCI at 12 tertiary care centers in Jordan between January 2013 and February 2014. A case report form was used to record data prospectively at hospital admission, discharge, and 12 months of follow-up. Mean age was 56 ± 11 years, females comprised 21% of the study patients, 62% had hypertension, 53% were diabetics, and 57% were cigarette smokers. Most patients (77%) underwent PCI for acute coronary syndrome. In-hospital and 1-year mortality rates were 0.78% and 1.94%, respectively. Definite or probable stent thrombosis occurred in 9 patients (0.37%) during hospitalization and in 47 (1.94%) at 1 year. Rates of target vessel repeat PCI and coronary artery bypass graft surgery at 1 year were 3.4% and 0.6%, respectively. The multivariate analysis revealed that cardiogenic shock, congestive heart failure, ST-segment deviation, diabetes, and major bleeding were significantly associated with higher risk of 1-year mortality.
Conclusions: In this first large Jordanian registry of Middle Eastern patients undergoing PCI, patients treated were relatively young age population with low in-hospital and 1-year adverse cardiovascular events. Certain clinical features were associated with worse outcomes and may warrant aggressive therapeutic strategies.