Reader Login| Users Online: 839  
Home Print this page Email this page Small font sizeDefault font sizeIncrease font size   
Home | About us | Editorial board | Search | Ahead of print | Current Issue | Archives | Submit article | Instructions | Subscribe | Advertise | Contact us
 
Export selected to
Endnote
Reference Manager
Procite
Medlars Format
RefWorks Format
BibTex Format
  Citation statistics : Table of Contents
   2011| July-September  | Volume 12 | Issue 3  
    Online since April 16, 2012

 
 
  Archives   Previous Issue   Next Issue   Most popular articles   Most cited articles
 
Hide all abstracts  Show selected abstracts  Export selected to
  Cited Viewed PDF
ORIGINAL ARTICLES
Effects of Combined Early In-Patient Cardiac Rehabilitation and Structured Home-based Program on Function among Patients with Congestive Heart Failure: A Randomized ontrolled Trial
Abraham Samuel Babu, Arun G Maiya, M Milton George, Ramachandran Padmakumar, Vasudeva Guddattu
July-September 2011, 12(3):99-103
DOI:10.4103/1995-705X.95064  PMID:22567195
Aims: To determine the effects of combined in-patient rehabilitation with a home-based program on function and quality of life. Setting and Design: Tertiary care, university teaching hospital, randomized controlled trial. Patients and Methods: Thirty admitted patients with congestive heart failure with New York Heart Association class II -IV. A five step individualised phase-1 cardiac rehabilitation program followed by a structured home based rehabilitation for eight weeks was given to the experimental group while the control group only received physician directed advice. Six minute walk distance was assessed at discharge and follow-up, while quality of life (SF36) was assessed at admission, discharge, and follow-up. Statistical analysis used: Independent t-test, paired t-test and repeated measures ANOVA with Bonferroni post-hoc analysis. Results: At admission patients in both the groups were comparable. After the phase-1 cardiac rehabilitation, there was a change in the six minute walk distance between control and experimental group (310 m vs. 357 m, respectively; P = 0.001). Following the eight week home-based program, there was a greater increase in six minute walk distance in the experimental group when compared to the control group (514 m vs. 429 m; P < 0.001). Quality of life as measured by the SF-36 at the end of 8-weeks showed a statistically significant difference (P < 0.05) in the experimental group for both the mental and physical components. Conclusion: Early in-patient rehabilitation followed by an eight week home based exercise program improves function and quality of life in patients with congestive heart failure.
  13 5,199 335
HISTORY OF MEDICINE
Statins: Past and Present
Rachel Hajar
July-September 2011, 12(3):121-127
DOI:10.4103/1995-705X.95070  PMID:22567201
  5 3,725 187
ORIGINAL ARTICLES
Mild Functional Ischemic Mitral Regurgitation Following Acute Coronary Syndrome: A Retrospective Study
Sadip Pant, Pritam Neupane, Om Biju Pant, Raju Paudel, MP Kavin Kumar, CS Vijayashankar, Rajendra Man Shrestha
July-September 2011, 12(3):93-98
DOI:10.4103/1995-705X.95063  PMID:22567194
Background: Ischemic mitral regurgitation is a frequent complication of acute coronary syndrome. It primarily occurs in patients with a prior myocardial infarction but also may be seen with acute ischemia, a setting in which the MR typically resolves after the ischemia resolves.none The vast majority of patients have "functional" ischemic MR. In these individuals, the papillary muscles, chordae, and valve leaflets are normal. However, the leaflets do not coapt and restricted leaflet motion is frequently noted on echocardiography. Ischemic mitral regurgitation indicates a poor prognosis after acute myocardial infarction. This study addresses the clinical characteristics of patients of acute coronary syndrome with mild functional ischemic mitral regurgitation and its impact on immediate in-hospital cardiovascular outcomes and death. Patients and Methods: From March 2006 through May 2007, patients who underwent 2-dimensional (2D) color doppler echocardiographic quantification of ischemic mitral regurgitation within 10 days of admission for acute coronary syndrome (ACS) in Manipal Teaching Hospital, a tertiary hospital in the western region of Nepal were noted. The demographic details, conventional risk factors of coronary artery disease, clinical and laboratory findings, treatment course and in-hospital outcomes of all the patients with mild functional ischemic MR following ACS in that time duration were recorded in a designated Performa. A total of 94 patients enrolled in the study were divided into two groups: Group I with mild functional ischemic MR and Group II without MR on 2D echocardigraphic assessment. Patient characteristics, risk factors, ejection fraction, and cardiovascular outcome and death among the two groups were compared and analyzed using software package SPSS 17.0 version. Results : Group I constituted 64.89% of the study population and Group II comprised of 35.11%. The patients in Group I was more likely to be elderly diabetic (P<0.05), and smokers with hypertension (P < 0.05). Mild functional ischemic MR was more common in patients with STEMI as compared to those with unstable angina and NSTEMI (55.7%, 36.1%, and 8.2%; P < 0.05).The mean ejection fraction in the first group was 54.84% in contrast to 58.92% observed in group II (P < 0.05).The type of wall involvement inferred from EKG analysis was homogeneously distributed in both the groups. Finally, there was no difference in immediate in-hospital (within 10 days) mortality or cardiovascular outcomes (heart failure, ventricular tachycardia/fibrillation, hypotension, and cardiogenic shock) between these two groups. Conclusion: Ischemic mitral regurgitation following acute coronary syndromeare more likely in elderly diabetics and hypertensive smokers. It is a more common finding in STEMI. Although mild MR following ACS does reduce ejection fraction, the immediate (within 10 days) in-hospital mortality and cardiovascular outcomes are not significantly altered.
  4 2,917 170
PERSPECTIVE
Statin Hepatotoxicity: Is it a Real Concern?
Pranav Sikka, KK Saxena, Seema Kapoor
July-September 2011, 12(3):104-106
DOI:10.4103/1995-705X.95065  PMID:22567196
Statins are the most effective and widely used drugs for treating dyslipidemia, a major risk factor for coronary heart disease. These are one of the safest hypolipidemic drugs but many patients are advised to discontinue statins for the fear of hepatotoxicity. Despite a lack of evidence that statins cause liver diseases, many physicians are reluctant to start statins in patients with an out-of-range liver enzymes value and this reluctance to initiate or interrupt the therapy with statins leads to dyslipidemia and its grave consequences. Further, there are some reports showing an additional benefit of statins in reducing cardiovascular events in patients with abnormal liver function tests.
  3 2,480 161
CASE REPORTS
A Rare Case of Situs Inversus with Dextrocardia, Lutembacher Syndrome, and Pericardial Effusion
Vishakha V Jain, OP Gupta, Jyoti Jain
July-September 2011, 12(3):107-111
DOI:10.4103/1995-705X.95066  PMID:22567197
Incidence of congenital cardiac anomalies in dextrocardia with situs inversus is low as compared to congenital cardiac anomalies in isolated dextrocardia. We describe the first ever case of situs inversus with dextrocardia, Lutembacher's syndrome, and pericardial effusion. The pericardial effusion in our case was acquired and was tubercular in etiology.
  2 4,163 169
Hypertrophic Cardiomyopathy in a Young Adult with RV Aneurysm: Report of a Rare Finding and Review of the Literature
Ahmed M Abdel-Razek, Leonard Y Lee, Robert Tozzi
July-September 2011, 12(3):112-117
DOI:10.4103/1995-705X.95067  PMID:22567198
We report a case of a 22-year-old patient with a severe form of hypertrophic cardiomyopathy involving both ventricles, for which he underwent surgical treatment. Echocardiogram and magnetic resonance imaging confirmed the presence of an aneurysm in the inferior-anterior portion of the right ventricle.
  1 3,435 109
A PICTURE IS WORTH A THOUSAND WORDS
Post Myocardial Infarction Left Ventricular Giant Pseudoaneurysm
Sudeep Kumar, Nagaraja Moorthy, Aditya Kapoor, Nakul Sinha
July-September 2011, 12(3):118-119
DOI:10.4103/1995-705X.95068  PMID:22567199
  - 1,871 115
ART AND MEDICINE
Medical Caricature
Rachel Hajar
July-September 2011, 12(3):120-120
DOI:10.4103/1995-705X.95069  PMID:22567200
  - 1,527 94
  Feedback 
  Subscribe