Login | Users Online: 98  
Home Print this page Email this page Small font sizeDefault font sizeIncrease font size   
Home | About us | Editorial board | Search | Ahead of print | Current Issue | Archives | Submit article | Instructions | Subscribe | Advertise | Contact us
 
MEDICAL WRITING
Year : 2001  |  Volume : 2  |  Issue : 1  |  Page : 16-19

Aggressive lipid lowering in patients with coronary heart disease


2nd Department of Medicine, Krankenanstalt Rudolfstiftung, Vienna, Austria

Correspondence Address:
Ronald Karnik
2nd Department of Medicine, Krankenanstalt Rudolfstiftung, Juchgasse 25, A-1030 Vienna
Austria
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Atherosclerosis is by far the most frequent cause of coronary heart disease (CHD). Large studies have provided unequivocal evidence that lipid lowering by statins significantly reduce the incidence of CHD endpoints. New insights in the pathophysiology show that statin therapy reduces progression of atherosclerosis, and leads to plaque stabilization as well as a reduced plaque thrombogenicity. In patients with CHD, treatment with statins may prevent plaque rupture of atherosclerotic lesions and therefore reduces the occurrence of acute coronary syndromes. Patients with hemodynamically relevant stenosis and angina interfering with quality of life and patients who have less exercise tolerance may be regarded as candidates for coronary intervention. In these patients, aggressive lipid-lowering may complement angioplasty by stabilizing untreated lesions. According to the guidelines of the National Cholesterol Educational Program, LDL-cholesterol of no more than 100mg/dl is considered optimal in patients with CHD or other atherosclerotic diseases.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed181    
    Printed2    
    Emailed0    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal