Login | Users Online: 96  
Home Print this page Email this page Small font sizeDefault font sizeIncrease font size   
Home | About us | Editorial board | Search | Ahead of print | Current Issue | Archives | Submit article | Instructions | Subscribe | Advertise | Contact us
 
ORIGINAL ARTICLE
Year : 2001  |  Volume : 2  |  Issue : 2  |  Page : 63-68

Surgical and pathology findings of primary malignanst cardiac tumors: An eleven year experience(*)


1 Department of Pathology, 2nd University of Naples, Naples, Italy
2 Department of Cardiothoracic Sciences, V. Monaldi Hospital, Naples, Italy

Correspondence Address:
Attilio Renzulli
Via Aquila 144, 80143 Naples
Italy
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Progress in cardiac imaging techniques allowed earlier diagnosis of malignant cardiac tumors. Between January 1978 and June 1999, 75 cases of primary heart tumours were surgically excised, 8 of them (10.67%) were malignant. They came from 4 males and 4 females, and with age ranging from 3 weeks to 70 years (mean 29); 3 tumours came from 3 infants (<1 year); the others developed in adult patients. All patients survived the surgical excision but died during the follow-up period. The histotypes were: 3 rhabdomyosarcomas (RMS), 2 malignant fibrous histiocytomas (MFH), 1 immature malignant intrapericardial teratoma, 1 fibrosarcoma and 1 mesothelioma. Among the 3 RMS, 2 were pleomorphic RMS (in the adult patients), located respectively in both atria and in the left ventricle and infiltrating the anterior papillary muscle; one (in a newborn) was an embryonal RMS of the anterior left ventricular wall spreading in the pericardium. MFH recurred twice in both patients; one patient died of post-operative complications after the second recurrence while the other patient died of heart failure 84 months after the first surgery. Also immature malignant intrapericardial teratoma recurred 2 months after the surgery; the newborn died of post-operative complications such as the newborn with fibrosarcoma. The mesothelioma occurred in an adult patient who died 5 months after the surgery. Despite complete surgical resection, which is initially successful, recurrence of tumor occurs and late mortality is still very high (100%). Our experience over a ten-year period confirms: a) the difficult differential diagnosis between primary sarcomas of the heart with other masses including secondary tumours and b) the relatively low incidence of heart malignancies in adults (10.95%) versus a higher incidence in childhood (37.5%).


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed184    
    Printed2    
    Emailed0    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal