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Year : 2012  |  Volume : 13  |  Issue : 4  |  Page : 139-145

Vulnerable plaque: From bench to bedside; local pacification versus systemic therapy

1 Cardiology Unit, Medical Faculty, UiTM Sg Buloh, Selangor, Malaysia; Division of Cardiology, Cork University Hospital, Cork, Ireland
2 Division of Cardiology, Cork University Hospital, Cork, Ireland

Correspondence Address:
Sazzli Kasim
Cardiology Unit, Medical Faculty, UiTM Sg Buloh, Selangor, Malaysia

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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1995-705X.105731

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Critical coronary stenoses accounts for a small proportion of acute coronary syndromes and sudden death. The majority are caused by coronary thromboses that arise from a nonangiographically obstructive atheroma. Recent developments in noninvasive imaging of so-called vulnerable plaques created opportunities to direct treatment to prevent morbidity and mortality associated with these high-risk lesions. This review covers therapy employed in the past, present, and potentially in the future as the natural history of plaque assessment unfolds.

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