| ORIGINAL ARTICLE |
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| Year : 2015 | Volume
: 16
| Issue : 2 | Page : 47-52 |
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Prevalence of chronic kidney disease and the incidence of acute kidney injury in patients with coronary artery disease in Mumbai, India
Pavan Malleshappa1, Bharat V Shah2
1 Department of Medicine, Division of Nephrology, Adichunchanagiri Institute of Medical Sciences, B. G. Nagara, Mandya, Karnataka, India
2 Department of Nephrology, Global Hospital, Mumbai, Maharashtra, India
Correspondence Address:
Dr. Pavan Malleshappa
Department of Medicine, Division of Nephrology, Adichunchanagiri Institute of Medical Sciences, B. G. Nagara, Nagamangala, Mandya, Karnataka
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1995-705X.159219
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Background and Objective: To determine the prevalence of chronic kidney disease (CKD) and incidence of acute kidney injury (AKI) in patients with coronary artery disease (CAD) demonstrated on coronary angiography.
Materials and Methods: Totally, 125 patients admitted to Lilavati Hospital and Research Centre, Mumbai, with CAD were included in the study.
Results: Left anterior descending artery was the major vessel involved (40%), followed by a circumflex artery (21.6%). 49 out of 125 (39.2%) were found to have underlying CKD. 69% (34) of these CKD patients developed AKI. 21 out of 34 patients who developed AKI required hemodialysis. Only 47.1% (16 out of 34) of CKD patients had complete recovery, 29% had partial recovery, and 23% had no recovery of their renal function from AKI. Statistically significant number of patients in CKD group had no recovery from AKI as compared to non-CKD group (23.5% vs. 0%).
Conclusion: Our study concludes that there is a very high prevalence of CKD (39.2%) in patients with CAD and AKI is a very important complication (38.4%) in these patients. Considering such a high prevalence of CKD, nephrology referral must be considered in patients with abnormal urinalysis, spot urinary protein to creatinine ratio and in patients whose creatinine clearance is <60 ml/min. |
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