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Year : 2021  |  Volume : 22  |  Issue : 1  |  Page : 30-34

Administration of protamine through radial arterial access: A prospective observational study

1 Department of Cardiac Anaesthesiology, M.M. Institute of Medical Science and Research, Mullana, Ambala, Haryana, India
2 All India Institute of Medical Sciences, New Delhi, India
3 Department of Cardiac Anesthesia, Sir Ganga Ram Hospital, New Delhi, India

Correspondence Address:
Dr. Monish S Raut
Department of Cardiac Anesthesiology, Sir Ganga Ram Hospital, New Delhi
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Source of Support: None, Conflict of Interest: None


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Protamine is mainly used to reverse the anticoagulant effect of heparin after cardiopulmonary bypass (CPB). Unfortunately, it is associated with adverse clinical reactions ranging from minor cardiopulmonary instability to fatal cardiovascular collapse. In the present prospective observational study, effects of protamine administration through peripheral intra-arterial route, i.e., radial artery, were investigated.

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