Smoking effect on ischemic heart disease in young patients :Khaled Hbejan, Heart Views

ORIGINAL ARTICLE
Year : 2011 | Volume : 12 | Issue : 1 | Page : 1--6

Smoking effect on ischemic heart disease in young patients

Khaled Hbejan
Department of Internal Medicine, Faculty of Medicine, Aleppo University, Aleppo University Heart Hospital, Syria

Correspondence Address:
Khaled Hbejan
Department of Internal Medicine, Faculty of Medicine, Aleppo University, Aleppo University Heart Hospital
Syria

Objective: To evaluate the effect of tobacco smoking on the risk of nonfatal acute myocardial infarction in young adults (≤45 years). Patient and Methods: We conducted a population-based case-control study with 329 incident acute myocardial infarction cases (42 women; 287 men), consecutively admitted to the Cardiology department of hospitals in Aleppo, Syria, and 778 controls (486 women; 292 men), selected within the noninstitutionalized Aleppo population, during 2008-2010. Odds ratios (OR) and 95% confidence intervals (95%CI) were calculated using unconditional logistic regression. Results: The prevalence of current smoking was 80.8% in male cases and 53.8% in male controls (OR = 3.63, 95%CI: 2.50, 5.27) and 59.5% of female cases were smokers compared with 35.8% of controls (OR = 2.64, 95%CI: 1.39, 5.02). No interaction was found between current smoking and gender on myocardial infarction risk (P = 0.401). A dose-effect response was present, the odds favoring myocardial infarction reaching an eight-fold increase for those who smoked >25 cigarettes/day compared with never smokers. The risk estimate for former smokers was similar to never smokers. Conclusions: Tobacco smoking is an important independent risk factor for acute myocardial infarction in young adults, with similar strength of association for both genders.

How to cite this article:
Hbejan K. Smoking effect on ischemic heart disease in young patients.Heart Views 2011;12:1-6

How to cite this URL:
Hbejan K. Smoking effect on ischemic heart disease in young patients. Heart Views [serial online] 2011 [cited 2023 Jun 10 ];12:1-6
Available from: https://www.heartviews.org/article.asp?issn=1995-705X;year=2011;volume=12;issue=1;spage=1;epage=6;aulast=Hbejan;type=0